News and Announcements
Center for Modeling Immunity to Enteric Pathogens galvanized for next phase of research
BLACKSBURG, Va., Dec. 16, 2011 – Virginia Bioinformatics Institute (VBI) researchers led by Dr. Bassaganya-Riera, Professor of Immunology at VBI and Director of the Nutritional Immunology and Molecular Medicine Laboratory (NIMML), returned from the Modeling Immunity for Biodefense (MIB) annual meeting galvanized to launch into Year Two of the Center for Modeling Immunity for Enteric Pathogens (MIEP) program. [More ...]
Healthy Volunteers Needed to Study Immune Responses to Intestinal Pathogens
BLACKSBURG, Va., September 28, 2011 – You may be interested in a clinical study the Center for Modeling Immunity to Enteric Pathogens (MIEP) is conducting. We Are Looking for Healthy Volunteers to Study Immune Responses to Intestinal Pathogens. Compensation is available if you qualify and are enrolled in the study. Please Contact (434) 924-9922 if you live near Charlottesville or (540) 231-7276 if you live near Blacksburg for more information. [More ...]
Press Releases
- Center for Modeling Immunity to Enteric Pathogens Releases a Revolutionary Modeling and Simulation Software: ENteric Immunity SImulator
- Center for Modeling Immunity to Enteric Pathogens Contributes Code to The Open Source Community
- Center for Modeling Immunity to Enteric Pathogens to Release New Website
- GBCB graduate student awarded National Institutes of Health fellowship to study diabetes and obesity
- Biomedical Computation Review: “Follow the Money: Big Grants in Biomedical Computing”
- Immune system changes linked to inflammatory bowel disease revealed
- Math model of colon inflammation singles out dangerous immune cells
Selected Publications
- Computational Modeling-Based Discovery of Novel Classes of Anti-Inflammatory Drugs That Target Lanthionine Synthetase C-Like Protein 2
- High-Performance Interaction-Based Simulation of Gut Immunopathologies with ENteric Immunity SImulator (ENISI)
- ENteric Immunity SImulator: A tool for in silico study of gut immunopathologies
- Modeling the Mechanisms of Action Underlying the Plasticity of the CD4+ T cell Differentiation Process
- Abscisic acid Regulates Inflammation via Ligand-Binding Domain-Independent Activation of PPAR gamma
- Immunoregulatory Mechanisms of Macrophage PPAR Gamma in Mice with Experimental Inflammatory Bowel Disease
Research Highlights
PPARγ Modulates the Plasticity between Th17 and iTreg
The MIEP team has created a network model of CD4+ T cell differentiation that reveals how the transcription factor peroxisome proliferator-activated receptor γ (PPARγ) modulates differentiation from Th17 to iTreg. [more ...]
